
Continuous pre-screening
Centrova checks your patient population against each active trial’s inclusion and exclusion criteria, and keeps checking as new labs, diagnoses, and visits arrive.

Centrova reviews your patient records against active trial criteria — surfacing likely-eligible patients, cutting manual screening, and helping your research team reach enrollment targets sooner.
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Most trial screening still happens by hand, one chart at a time. Centrova reviews eligibility continuously, so coordinators can spend their time with patients.

Centrova checks your patient population against each active trial’s inclusion and exclusion criteria, and keeps checking as new labs, diagnoses, and visits arrive.

Every trial gets a ranked list of likely-eligible patients with the matching criteria shown, so investigators can review each candidate quickly and with confidence.

Centrova reads structured and unstructured data from your EHR and research systems. No duplicate data entry, and no new spreadsheets to keep in sync.

Site leaders see enrollment progress, match volume, and time to enrollment across every active trial — in one view, updated daily.
Product tour
A walk through Centrova: a ranked shortlist in seconds, screening in parallel, the evidence behind every verdict, and every call kept with your team.
Teresa comes over already selected, and every patient in the panel gets a Potential Match % against the trials you're enrolling, in seconds. Sort, add the best fits, and go.
Click a score to see how the same patient stacks up against each selected trial, then send the whole shortlist to screening in one click.
Centrova reads each selected patient's chart as it stands today, dozens of notes apiece, all at once and criterion by criterion. Chart review that used to fill an afternoon comes back in minutes.
Flip to Confidence % to see how sure the model is on each row, so reviewers spend their time where it matters.
Click a verdict to see every passage behind it, across all of the patient's notes, highlighted in the original documents. If the AI cites wording the chart doesn't contain, the viewer says so.
Confirm or override any verdict with a written rationale, then submit the stage for PI review. Every decision stays on the record.
How it works
Results
The same screening, done by hand or with Centrova. Same clinical judgement, very different workload
See how pre-screening worksOne ranked queue per trial
One coordinator + a stack of charts
From the research
Figures from Centrova Research's reviews of the published evidence. Each one links to the article and its full sources.
55%
of cancer patients offered a trial agree to enroll.
Unger et al., JNCI, 2021 · 9,759 patients49%
of providers say they screen every patient for the trials open at their site.
Durden et al., Cancer, 2024 · 693 providers77%
of patients with a condition are excluded by trial eligibility criteria, at the median.
He et al., Trials, 2020 · 305 trials65%
of research sites report a shortage of clinical research coordinators.
Advarra industry survey, 2024Cost
Start with a pilot in one department, then expand across your site or health system. Every plan includes core matching and screening.
90-day pilot, one department
Prove the value in one department before you commit. Configured with your team, with no long-term contract.
based on # of patients and trials
For research sites running several trials at once and ready to make matching part of everyday screening.
tailored to your network
For health systems and academic medical centers running trials across multiple hospitals and departments.
Centrova reads each trial’s inclusion and exclusion criteria and compares them with the data in your patient records — diagnoses, medications, labs, procedures, and clinical notes. Every recommendation shows which criteria are met, which are not, and which still need confirmation. Your research team always makes the final eligibility decision.
Centrova is designed for HIPAA-regulated environments. Data is encrypted in transit and at rest, access is role-based and logged, and patient data is never used to train models shared across customers. We work under a Business Associate Agreement with each customer and are happy to walk your security, privacy, and compliance teams through our controls during evaluation.
Yes. Centrova connects to your EHR through standard interfaces such as HL7 FHIR or secure scheduled data extracts, and can work alongside your CTMS and eConsent tools. During onboarding we work with your IT and research informatics teams to agree exactly which data is shared and how often it refreshes.
Most sites start with a pilot in one department. Once data access is approved, a pilot is typically configured within a few weeks, with your first trials loaded and recommendations reviewed alongside your coordinators. The biggest factor in timing is usually your internal security and data-governance review, and we support that process throughout.
Centrova is used by research coordinators, principal investigators, and research leadership at hospitals, academic medical centers, and research sites. Sponsors and CROs can work with participating sites on feasibility and enrollment progress through aggregated, de-identified reporting — they never see identifiable patient information.
Integrations
EHR, CTMS, eConsent, lab systems, ClinicalTrials.gov, and single sign-on. Centrova works alongside the systems your research team already uses, through standard interfaces like HL7 FHIR.

Start with a pilot in one department. Centrova is onboarding a small group of early hospital and research-site partners this year.
Book a demo